Clinical cases

Metastatic Lobular Breast Carcinoma in a Lymph Node

Cytological features of metastatic lobular breast carcinoma in a lymph node: differential diagnosis from lymphoma and plasmacytoma, tumor immunophenotype.

🔬Metastasis of lobular breast carcinoma to a lymph node.

❗These cells somewhat resemble plasma cells… Therefore, be careful with your conclusions!

👉Cell phenotype: CK7+ GATA3+ ER+ PR- HER2-0, E-cadherin- (E-cadherin expression is lost in lobular carcinoma).

👉Images kindly provided by Clinical Laboratory Diagnostics Physician, Pathologist from Saint Petersburg Belyakova Elena Alexandrovna, Department of Clinical Molecular Morphology at E.E. Eichwald Clinic (Lymphoma Differential Diagnostics Center) of I.I. Mechnikov Northwestern State Medical University.