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Oncohematology

Multiple Myeloma: Bone Marrow Picture in Remission

Morphological remission in multiple myeloma: myelogram evaluation, 1.0% plasma cells, and complete blood count parameters in a 73-year-old female patient.

Nana Novikova Nana Novikova 1 min
Bone marrow smear: mature plasma cell with a perinuclear clear zone
Bone marrow smear: mature plasma cell with a perinuclear clear zone
Bone marrow smear: granulocytic and erythroid lineage cells
Bone marrow smear: granulocytic and erythroid lineage cells
Bone marrow smear: normoblasts and maturing granulopoiesis cells
Bone marrow smear: normoblasts and maturing granulopoiesis cells
Bone marrow smear: preserved granulocytopoiesis without excess plasma cells
Bone marrow smear: preserved granulocytopoiesis without excess plasma cells
Bone marrow smear: mature megakaryocyte with a lobulated nucleus and stromal cells
Bone marrow smear: mature megakaryocyte with a lobulated nucleus and stromal cells
Complete blood count form: hemoglobin 89 g/l and ESR acceleration to 52.19 mm/h
Complete blood count form: hemoglobin 89 g/l and ESR acceleration to 52.19 mm/h

Patient, 73 years old. Diagnosis: MULTIPLE MYELOMA.

The bone marrow picture appears calm. The lymphoid lineage is not expanded (10%). The lymphocyte content is 9.0% (normal 4.3-13.7), plasma cells - 1.0% (normal 0.4-1.8%).

In the CBC, there is mild anemia. Photo 1 shows a mature plasma cell with a distinct, eccentrically located nucleus, basophilic cytoplasm with a perinuclear clear zone.

The picture corresponds to morphological remission of the disease.

🙏 The publication was kindly provided by KDL physician Nana Novikova, CHUZ “KB” RZHD-Meditsina" Smolensk.

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