Erythrocytes lose the clarity of their cell membrane contour, acquiring a deformed shape.
The cause of this change is an excess of lipids, which disrupts the lipoprotein composition balance of the erythrocyte membrane.
This phenomenon is observed in patients with elevated lipid levels, particularly in hyperlipidemia, when the concentration of triglycerides in blood serum exceeds 1000 milligrams per deciliter. In such cases, these cells are found in peripheral blood smears.
🔬 Source: from the archive of Brazilian hematology specialist Marcio Melo
