Hematology

Cell Morphology: A Diagnostic Microscopy Challenge

A cell morphology challenge: identify the origin of cells with cytoplasmic projections forming clusters in a microscopic preparation.

Microscopic preparation for the cell morphological classification exercise
Microscopic preparation for the cell morphological classification exercise

We received a microscopic preparation with cells requiring classification.

These cells had cytoplasmic projections and were predominantly arranged in clusters.

What are these cells?

  1. Hairy cells
  2. Villous cells
  3. Endothelial cells

🔬 Source: from the archive of Brazilian hematology specialist Marcio Melo