Oncohematology

Mantle Cell Lymphoma Cell Morphology in Blood

Learn about the morphological features of mantle cell lymphoma cells in peripheral blood smears: size, chromatin structure, nucleoli, and cytoplasm of CD5+ B-cells.

Blood smear: atypical lymphoid cells in mantle cell lymphoma
Blood smear: atypical lymphoid cells in mantle cell lymphoma

Mantle cell lymphoma cells in peripheral blood. Mantle cell lymphoma is a CD5-positive B-cell lymphoma. The cells are small to medium-sized with mature chromatin, usually with a visible nucleolus and varying amounts of cytoplasm. Mantle cell lymphoma can have a variable disease course, from indolent to aggressive. ✅ Source: inst:pathnuggets