🩸Bone marrow with signs of
🔹Dysgranulocytopoiesis:
➖ neutrophil nuclear hypersegmentation (photos 1-4) ➖gigantism, bizarre neutrophil nuclei (photos 1, 5) ➖anisocytosis of the granulocytic lineage (photos 1-2) ➖ring forms of neutrophil nuclei (photo 6)
🔸Erythroid lineage:
➖ Presence of intercellular bridges (photo 7) ➖Anisocytosis towards macroforms (photos 1, 8) ➖ Incomplete stage of mitotic division (photo 4)
🧐A diagnosis of severe B12 deficiency anemia was made. Positive dynamics were noted against the background of ongoing vitamin B12 therapy.
🙏 The publication was kindly provided by Clinical Laboratory Diagnostics Doctor Tanya Stepanova, Volgograd
