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Oncohematology

Blood Smear Morphology in Primary Myelofibrosis

A clinical case of primary myelofibrosis with JAK2 V617F mutation: analysis of analyzer hemogram, leucoerythroblastic picture, dacryocytes, and cell atypia.

Anna Belen Anna Belen 1 min
Hematology analyzer printout: anemia and high RDW 22.7%
Hematology analyzer printout: anemia and high RDW 22.7%
Blood smear: atypical mononucleated cell, pronounced poikilocytosis and dacryocytes
Blood smear: atypical mononucleated cell, pronounced poikilocytosis and dacryocytes
Blood smear: pseudo-Pelger-Huët neutrophil, lymphocyte, and tear-drop cells
Blood smear: pseudo-Pelger-Huët neutrophil, lymphocyte, and tear-drop cells
Blood smear: monocytes with cytoplasmic vacuolization and erythrocyte poikilocytosis
Blood smear: monocytes with cytoplasmic vacuolization and erythrocyte poikilocytosis
Blood smear: segmented neutrophil, anisocytosis, and single platelets
Blood smear: segmented neutrophil, anisocytosis, and single platelets
Blood smear: basophilic stippling in erythrocyte and giant platelets
Blood smear: basophilic stippling in erythrocyte and giant platelets
Blood smear: arrow points to an oxyphilic normoblast against a background of poikilocytosis
Blood smear: arrow points to an oxyphilic normoblast against a background of poikilocytosis
Blood smear: arrow indicates a normoblast, a myeloid precursor is visible at the top
Blood smear: arrow indicates a normoblast, a myeloid precursor is visible at the top
Blood smear: arrow shows a normoblast, pronounced tear-drop deformation
Blood smear: arrow shows a normoblast, pronounced tear-drop deformation

🩸Blood smear with rich morphology! A case from Israel🇮🇱 ✅A 70-year-old male with primary myelofibrosis with a positive V617F mutation in the JAK2 gene. Complete blood count in the photo. ✅We invite you to comment on pathological findings/changes. ✅What is indicated by the arrow? ✅Will anyone find the infinity sign?

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