Hematology

Megakaryocyte Morphology and Emperipolesis in Bone Marrow

Normal megakaryocyte morphology in bone marrow: multilobed nucleus, signs of emperipolesis in the cytoplasm, and platelet formation.

Bone marrow smear: mature megakaryocyte with signs of emperipolesis
Bone marrow smear: mature megakaryocyte with signs of emperipolesis

Normal morphology megakaryocyte with a multilobed nucleus and pinkish cytoplasm, in which signs of emperipolesis are observed. Each megakaryocyte can give rise to approximately 1200 platelets.

Sample type Bone marrow.

Staining type May-Grünwald-Giemsa.

Authors Cristina de la Fuente Montes, José Tomás Navarro Ferrando, Rebeca Jurado Tapiador.

Workplace Hematology Laboratory Department. Catalan Institute of Oncology - HGTiP - Josep Carreras Research Institute. Badalona, Spain.