Oncohematology

Myeloblast Morphology in Peripheral Blood Smear

Morphological features of myeloblasts: nucleus structure, nucleoli, cytoplasmic granules, and the necessity of immunophenotyping for differential diagnosis.

Blood smear, granulated blast (myeloblast) with nucleoli in the nucleus
Blood smear, granulated blast (myeloblast) with nucleoli in the nucleus

The correct answer to the Laboratory Hematologists Closed Club challenge. B. Myeloblast. Explanation: Myeloblasts are characterized by granules of the described size, an oval or round nucleus with 2–5 nucleoli, a dark violet nucleus, moderately condensed chromatin, and medium blue cytoplasm, which corresponds to the description. We remind you that based on morphology, we can only hypothesize the type of blast. Immunophenotyping is recommended. 🏆 Congratulations to the winners! 👉To join the closed group of laboratory hematologists, winners simply need to write to the instructor: “I want to join the selected club of specialists.” Then, Evgeny Gennadievich will send a private invitation in response. WRITE TO THE INSTRUCTOR→ The winners of this week’s challenge are:

✅ Laizhit Budazhapova ✅ Maria Eliseeva-Shatskikh ✅ Elena Pershikova