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Oncohematology

Acute Leukemia in a Child: Blast Morphology in Blood Smear

Clinical case of leukocytosis up to 85×10⁹/L and thrombocytopenia in a 9-year-old child. Sysmex analyzer results and blast cell morphology in a blood smear.

Irina Selivanova Irina Selivanova 1 min
Analyzer printout: leukocytosis 85.08×10⁹/L, thrombocytopenia, and WBC pathology flag
Analyzer printout: leukocytosis 85.08×10⁹/L, thrombocytopenia, and WBC pathology flag
Blood smear: blast cells with high N:C ratio and shadows of destroyed leukocytes
Blood smear: blast cells with high N:C ratio and shadows of destroyed leukocytes
Blood smear: cluster of blasts with delicate chromatin and a narrow rim of cytoplasm
Blood smear: cluster of blasts with delicate chromatin and a narrow rim of cytoplasm
Blood smear: polymorphic population of blast cells in the microscope field of view
Blood smear: polymorphic population of blast cells in the microscope field of view
Blood smear: blast with basophilic cytoplasm and shadows of destroyed cells
Blood smear: blast with basophilic cytoplasm and shadows of destroyed cells
Blood smear: group of blasts with irregular nuclear contours and indistinct nucleoli
Blood smear: group of blasts with irregular nuclear contours and indistinct nucleoli
Blood smear: blast cells next to a neutrophilic granulocyte
Blood smear: blast cells next to a neutrophilic granulocyte
Blood smear: blasts with nucleoli and a Botkin-Gumprecht shadow in the center
Blood smear: blasts with nucleoli and a Botkin-Gumprecht shadow in the center
Blood smear: pronounced blastosis with the formation of small cell clusters
Blood smear: pronounced blastosis with the formation of small cell clusters
Blood smear: monomorphic infiltration by blast cells on low-power microscopy
Blood smear: monomorphic infiltration by blast cells on low-power microscopy

A 9-year-old child. Complaints: lethargy, fatigue.

🙏 Images kindly provided by Clinical Laboratory Diagnostics Physician, Irina Selivanova LLC “Citilab-Ural”, Yekaterinburg

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