Oncohematology

Acute Myeloid Leukemia M2: Myelogram in FLT3-ITD

Clinical case of resistant AML (FAB-M2) with FLT3-ITD mutation. Bone marrow morphology: 23% blasts, dyserythropoiesis, micromegakaryocytes.

Acute myeloid leukemia, (M2), resistant course Material - bone marrow. The patient underwent 2 courses of chemotherapy without achieving remission; an ITD mutation in the FLT3 gene was detected. A third course of therapy has been initiated. In the myelogram, blasts up to 23% are found, micromegakaryocytes are present, and signs of dyserythropoiesis are noted in the erythroid lineage - intererythroid cytoplasmic bridges.

🙏 The publication was kindly provided by Ekaterina Nozdrina, Omsk.