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Oncohematology

Acute Undifferentiated Leukemia: Blast Morphology

A clinical case of acute undifferentiated leukemia: hyperleukocytosis, 88% blasts in blood, negative cytochemistry, and flow cytometry data.

Ekaterina Nozdrina Ekaterina Nozdrina 1 min
Blood smear: undifferentiated blast cells with a narrow rim of cytoplasm
Blood smear: undifferentiated blast cells with a narrow rim of cytoplasm
Blood smear: cluster of round blasts with delicate chromatin structure
Blood smear: cluster of round blasts with delicate chromatin structure
Blood smear: blast elements with basophilic cytoplasm and nucleoli
Blood smear: blast elements with basophilic cytoplasm and nucleoli
Blood smear: blast cells and a disintegrated leukocyte in the field of view
Blood smear: blast cells and a disintegrated leukocyte in the field of view
Blood smear: chain of three monomorphic blasts in peripheral blood
Blood smear: chain of three monomorphic blasts in peripheral blood
Blood smear: pronounced blastosis and disintegrating cellular elements
Blood smear: pronounced blastosis and disintegrating cellular elements
Analyzer printout: leukocytosis 89.73×10⁹/L, anemia, and thrombocytopenia 47×10⁹/L
Analyzer printout: leukocytosis 89.73×10⁹/L, anemia, and thrombocytopenia 47×10⁹/L

Newly diagnosed acute leukemia. 88% blasts in peripheral blood. Cytochemical reactions are negative. Myelogram shows 76% blasts. Immunophenotyping revealed an acute undifferentiated leukemia phenotype. Treatment has been initiated.

🙏 Publication kindly provided by Ekaterina Nozdrina, Omsk.

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