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Oncohematology

Acute Promyelocytic Leukemia: Promyelocyte Morphology

Morphological features of abnormal promyelocytes in acute promyelocytic leukemia (APL M3): butterfly-wing nuclei and marked hyperleukocytosis.

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Blood smear: abnormal promyelocytes with bilobed nuclei in AML M3
Blood smear: abnormal promyelocytes with bilobed nuclei in AML M3
Blood smear: hypergranular blast cells with cleaved nuclei
Blood smear: hypergranular blast cells with cleaved nuclei
Peripheral blood smear: marked leukocytosis and atypical promyelocytes
Peripheral blood smear: marked leukocytosis and atypical promyelocytes

“BUTTERFLY WINGS” Male patient, 21 years old, 220 thousand leukocytes. Hypergranular blasts (abnormal promyelocytes) with “Butterfly Wings” nuclear morphology, observed in promyelocytic leukemia - AML - M3 Source:inst:hematoon

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