Laboratory methods
RBC Clog and RBC Bubbles Flags on Hematology Analyzer
Causes of RBC Clog and RBC Bubbles flags on a hematology analyzer: volumetric measurement principle, count time control, and aperture burn.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Lab test interpretation
Active Leukocytes in Urine: Sternheimer-Malbin Cells
Supravital staining method by Pytel and Shapiro for detecting active leukocytes (Sternheimer-Malbin cells) in urine sediment in pyelonephritis.
Hematology
Leukocyte Differential and Left Shift in Sepsis
Clinical case: changes in complete blood count, Sysmex XN scattergrams, and cell morphology in severe sepsis with procalcitonin 289 ng/mL.
Parasitology
Enterobius vermicularis Eggs in Cervical Smear
Morphology of Enterobius vermicularis eggs in Papanicolaou-stained endocervical smears: differential diagnosis and causes of contamination.
Oncohematology
Acute Promyelocytic Leukemia: Morphology and Markers
A clinical case of acute promyelocytic leukemia: pancytopenia, blasts, CD34- and HLA-DR- immunophenotype, myeloperoxidase cytochemistry, and management strategy.
Oncohematology
Mantle Cell Lymphoma Cell Morphology in Blood
Learn about the morphological features of mantle cell lymphoma cells in peripheral blood smears: size, chromatin structure, nucleoli, and cytoplasm of CD5+ B-cells.
Lab test interpretation
Charcot-Leyden Crystals in Stool Microscopy
Detection of Charcot-Leyden crystals in stool microscopy with Lugol's solution. Clinical significance of eosinophil breakdown products in coprograms.
Hematology
Fanconi Anemia in an Adult: Blood Smear Morphology
A clinical case of Fanconi anemia in a 44-year-old patient: marked poikilocytosis, neutrophil hypersegmentation, and high RDW in a peripheral blood smear.
Lab test interpretation
Undigested Plant Fiber in Coprogram: Sea Buckthorn Berries
Fecal microscopy: undigested plant fiber from sea buckthorn berries in a coprogram. Morphological features of plant elements during analysis.
Parasitology
Demodex Mite in Dog Skin Neoplasm Aspirate
Accidental finding of a Demodex mite during microscopy of a cytological aspirate from a canine skin neoplasm. Romanowsky-stained preparation.
Lab test interpretation
Cholesterol Crystals in Coprogram: Microscopic Examination
Morphology of cholesterol crystals in stool during microscopic examination. Causes of detection and diagnostic significance in coprograms.
Clinical cases
Medullary Thyroid Carcinoma: Cytological Features
Cytological features of the giant cell variant of medullary thyroid carcinoma: multinucleated giant cells and nuclear polymorphism in aspirate.