Laboratory methods
Dicentromeric Chromosome: Definition and Formation Mechanism
What is a dicentric (dic) in cytogenetics? Structural features of a dicentric chromosome with two centromeres and translocation mechanisms.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Lab test interpretation
Tyrosine Crystals in Urine: Sediment Microscopy
Urine sediment microscopy: detection and morphology of tyrosine crystals as characteristic needle-like bundles and rosettes in severe liver damage.
Hematology
Differentiation of Atypical Cells in Blood Smear
Clinical case: differential diagnosis of cells in a blood smear from a 45-year-old man during a medical examination. Hematology analyzer data and microscopy.
Laboratory methods
Sperm Viability: Eosin-Nigrosin Staining Method
Method for assessing sperm viability using eosin-nigrosin staining. Differentiating live and dead cells in a spermogram during microscopy.
Oncohematology
Canine Acute Lymphoid Leukemia: Blast Morphology
A clinical case of acute lymphoid leukemia in a dog: hyperleukocytosis 132.6 K/µL, pancytopenia, blastemia, and frequent mitotic figures in a blood smear.
Parasitology
Morphology of Diphyllobothrium latum (Broad Tapeworm)
Explore the morphology of Diphyllobothrium latum: macroscopic view of the strobila, rosette-shaped uterus with eggs in mature proglottids, and the scolex of the broad tapeworm under the microscope.
Lab test interpretation
Leukocytes in Stool: Mononuclear Cell Microscopy
Morphology of leukocytes in stool. Microscopic detection of mononuclear cells and bacterial flora in a stool sample stained with methylene blue.
Parasitology
Cutaneous Leishmaniasis: Morphology of Leishmania major and Diagnostics
A clinical case of cutaneous leishmaniasis in an 18-year-old patient: detection of Leishmania major by PCR, smear microscopy of the ulcer, and cytomorphology of amastigotes.
Lab test interpretation
Morphology of Immature Spermatozoa in Spermogram
Morphological features of immature spermatozoa and spermatogenic cells in an ejaculate smear during microscopic analysis with hematoxylin and eosin staining.
Oncohematology
Hodgkin Lymphoma: Cytology of Lymph Node Imprint Smear
Cytological features of a lymph node imprint smear in Hodgkin lymphoma, mixed cellularity variant: Berezovsky-Reed-Sternberg cells and reactive background.
Oncohematology
Hairy Cell Leukemia and Chronic Lymphocytic Leukemia
A clinical case of simultaneous detection of hairy cell leukemia and a CLL cell population. Immunophenotyping and blood smear morphology.
Oncohematology
Mixed Cellularity Hodgkin Lymphoma: Lymph Node Cytology
Cytological features of a lymph node imprint smear in mixed cellularity Hodgkin lymphoma: Berezovsky-Sternberg cells within a polymorphic infiltrate.