Laboratory methods
Karyotyping: Cytogenetic Analysis of Chromosomes
Cytogenetic study and karyotyping: detection of t(9;22) translocation in CML and trisomy 21 on metaphase plates.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Hematology
Hematology Case: Identifying Cells in a Blood Smear
A diagnostic challenge in blood smear microscopy for a 41-year-old woman. Evaluate leukocyte morphology, analyzer data, and the DIFF scattergram.
Lab test interpretation
Alternaria Fungal Spores in Urine Sediment Microscopy
Learn to identify Alternaria fungal spores in urine sediment. Understand why finding conidia is an artifact with no diagnostic significance.
Lab test interpretation
Calcium Phosphate Crystals in Urine Sediment: Morphology
Morphology of calcium phosphate crystals in urine sediment microscopy: differentiation of dibasic and monobasic forms, rosettes, needles, and plates.
Oncohematology
Distinguishing Prolymphocytes from Blasts in CLL
A clinical case of marked leukocytosis in CLL. Morphological criteria for differentiating prolymphocytes from blast cells in a peripheral blood smear.
Lab test interpretation
Drug Crystals in Coprogram: Identification and Differential Diagnosis
Morphology of drug crystals during fecal microscopy in coprogram: features of identification and differential diagnosis of elements.
Lab test interpretation
Urinary Casts in Renal Failure: A Case of Massive Cylindruria
Microscopy of urine sediment: massive cylindruria in a 14-year-old patient with chronic renal failure. Morphology and diagnostic significance of casts in renal insufficiency.
Parasitology
Entamoeba Histolytica Trophozoites in Stool Sample
Microscopic identification of Entamoeba histolytica trophozoites in a wet mount stool sample stained with Lugol's iodine solution.
Oncohematology
Equine Eosinophilic Myeloproliferative Disease
Morphology of eosinophils in a horse blood smear with myeloproliferative disease: nuclear hyposegmentation and physiological features of erythrocytes.
Hematology
Morphology of Giant Nucleated Axolotl Erythrocytes
Morphology of axolotl (Ambystoma mexicanum) erythrocytes: giant nucleated cells with dense chromatin and an average MCV of 8000–12000 fL.
Lab test interpretation
Urine Sediment Microscopy: Crystalluria and Tumor Cells
Peculiarities of urine sediment microscopy: detection of calcium oxalate crystals in general clinical analysis and adenocarcinoma cells in cytology.
Parasitology
Chagas Disease: Trypanosoma cruzi in a Blood Smear
A case of Trypanosoma cruzi trypomastigotes detected in a peripheral blood smear of a newborn. Morphology of the Chagas disease pathogen and diagnosis.