Lab test interpretation
Cystine Crystals in Urine Sediment in Cystinuria
Characteristic hexagonal cystine crystals in acidic urine sediment: microscopic features, formation mechanism, and clinical significance in cystinuria.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Hematology
Green Crystals of Death in Neutrophils During Sepsis
Morphology of green crystals of death in neutrophils: the significance of blue-green inclusions, Döhle bodies, and bacteremia in severe sepsis.
Clinical cases
Hürthle Cells in Hashimoto's Thyroiditis: FNA Cytology
Cytological findings of a fine-needle aspirate of the thyroid gland in Hashimoto's thyroiditis: Hürthle cell clusters with atypia and lymphoid infiltration.
Lab test interpretation
Neutral Fat in Stool: Microscopy in Steatorrhea
Microscopic appearance of neutral fat in stool in steatorrhea: comparison of native preparation and methylene blue staining in coprogram.
Parasitology
Antiparasitic Immunity: Role of Eosinophils and IgE
Mechanisms of antiparasitic immune response: role of Th2 lymphocytes, IgE secretion, and activation of eosinophils with release of cytotoxic granule proteins.
Oncohematology
Megakaryocyte in Blood in Primary Myelofibrosis
Clinical case of primary myelofibrosis: dysplastic megakaryocyte, dacryocytes, and blasts found in peripheral blood, JAK2 V617F mutation.
Laboratory methods
Aspergillus niger Identification: Colony Morphology
Cultivation and micromorphology of Aspergillus niger: colony growth on Sabouraud agar and conidiophore structure under microscopy.
Hematology
Cold Agglutination in Complete Blood Count: A Case Study
A case of cold agglutination: false MCHC elevation, sample appearance in tube and microscopy, and parameter correction after 37°C incubation.
Laboratory methods
Preanalytical Stage of Urinalysis: Collection and Delivery Rules
The importance of the preanalytical stage in general urinalysis: rules for biomaterial collection, transportation conditions to the laboratory, and common errors.
Lab test interpretation
Yeast Fungi in Coprogram: Mycelium and Spores
Microscopic examination of stool with Lugol's solution: detection of mycelial filaments and clusters of yeast spores in a child with COVID-19.
Oncohematology
Blood Smear Morphology in Primary Myelofibrosis
A clinical case of primary myelofibrosis with JAK2 V617F mutation: analysis of analyzer hemogram, leucoerythroblastic picture, dacryocytes, and cell atypia.
Hematology
Chédiak–Higashi Syndrome: Neutrophil Morphology
Learn about Chédiak–Higashi Syndrome: LYST gene mutation, giant granules in neutrophils on blood smear microscopy, and partial albinism.