Parasitology
Tapeworm Diagnosis in Stool: A Clinical Case
A clinical case of a rare tapeworm identified by microscopy of a native stool sample in a child with chronic diarrhea and anemia.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Hematology
Counting Band Neutrophils in Blood Smears: Why It Matters
Why determine band neutrophils in the leukocyte formula: diagnosis of sepsis and SIRS, the link between band shift and mortality risk.
Lab test interpretation
Vitamin D-Deficient Rickets in an Adolescent: A Clinical Case
A clinical case of vitamin D-deficient rickets in an adolescent misdiagnosed as arthritis: 25(OH)D, parathyroid hormone, and alkaline phosphatase in diagnosis.
Lab test interpretation
Critical Hypoglycemia & Errors in Biochemistry Reports
We discuss critical blood glucose levels, the consequences of severe hypoglycemia, and post-analytical errors in biochemical analysis reports.
Hematology
Neutrophil Phagocytosis of Bacteria in Bacteremia
A clinical case of bacteremia: detection of rod-shaped bacteria phagocytosed by neutrophils during digital microscopy of a peripheral blood smear.
Laboratory methods
Romanowsky Staining of Blood Smears: Method History
The history of polychromatic blood smear staining: contributions of D. L. Romanowsky and Ch. I. Khentsinsky, mechanism, and ICSH recognition.
Oncohematology
Blood Smear Morphology in Primary Myelofibrosis
Peripheral blood smear findings in primary myelofibrosis: leucoerythroblastosis, dacryocytes, micromegakaryocytes, and giant platelets on microscopy.
Laboratory methods
DNA Molecule Structure: Fundamentals of Molecular Genetics
Features of DNA double helix structure, principles of genetic material organization, and molecular diagnostic methods in the clinical laboratory.
Hematology
Differential Diagnosis of Iron Deficiency and B12 Anemia
A clinical case review: differentiating microcytic iron deficiency anemia and vitamin B12 deficiency based on MCV and ferritin levels.
Hematology
Cell Nucleus Chromatin Patterns: Descriptive Terminology
How to describe chromatin structure in the cell nucleus: English classification of patterns and terminology options in Russian laboratory practice.
Oncohematology
KMT2A Gene Rearrangements in Acute Myeloid Leukemia
Genetic rearrangements of the KMT2A gene in acute myeloid leukemia: spectrum of partner genes according to the WHO 5th edition classification (WHO 2022).
Lab test interpretation
Diagnosing Pediatric Arterial Hypertension: An Algorithm
An algorithm for the differential diagnosis of secondary arterial hypertension in children, including laboratory and instrumental search criteria.