Lab test interpretation
Algorithm for Differential Diagnosis of Hypomagnesemia
A laboratory algorithm for the differential diagnosis of hypomagnesemia based on the assessment of urinary magnesium excretion, extrarenal, and renal losses.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Laboratory methods
Light Microscopy of Blood Smears in Field Conditions
Learn the specifics of performing light microscopy in field conditions. This guide covers smear preparation, microscope operation, and diagnostics outside the laboratory.
Oncohematology
Mitotic Figures and Dyserythropoiesis in MDS with Excess Blasts
Clinical case of MDS with excess blasts: bone marrow erythroblast morphology, multinuclearity, atypical mitotic figures, and micronuclei formation.
Education
Clinical Laboratory Diagnostics: A Day in the Life
A look into the daily work of clinical diagnostic laboratory specialists: smear microscopy, automated hematology analyzers, and lab workstation organization.
Parasitology
Pulmonary Corpora Amylacea: Morphology and Diagnosis
Corpora amylacea in pulmonary alveoli: morphological features, resemblance to parasites, and differential diagnosis in histology.
Hematology
Osteoclasts in Bone Marrow Aspirate: Differential Diagnosis
Morphological features of osteoclasts in bone marrow aspirate. Differential diagnosis of multinucleated osteoclasts and megakaryocytes in a smear.
Oncohematology
Acute Promyelocytic Leukemia: Hypogranular Variant M3v
Morphology of atypical promyelocytes in hypogranular acute promyelocytic leukemia M3v: bilobed nuclei resembling butterfly wings in bone marrow.
Laboratory methods
Purified DNA Solution: Causes of High Viscosity
Why purified genomic DNA solutions are highly viscous: physicochemical properties of eukaryotic DNA molecules in the clinical laboratory.
Hematology
LE Cells in Blood Smear: Morphology and Formation
What LE cells are in systemic lupus erythematosus: morphological signs of nuclear material phagocytosis by neutrophils in a blood smear.
Hemostasis
Hypercoagulation in Pregnancy by Thrombodynamics
Clinical case analysis: moderate hypercoagulation detected by thrombodynamics in a pregnant woman at 28 weeks. Thrombophilia screening algorithm.
Hematology
Secondary Erythrocytosis in Heart Defect: Hemoglobin 258 g/L
A clinical case of severe secondary erythrocytosis in a patient with a heart defect: hemoglobin level 258 g/L, hematocrit 76%, and erythrocytes 7.60×10¹²/L.
Oncohematology
Chronic Neutrophilic Leukemia: Bone Marrow Aspirate
A clinical case of chronic neutrophilic leukemia: hyperleukocytosis, granulocyte hyperplasia, and phagocytosis of nuclear debris by bone marrow macrophages.