Oncohematology
Clinical Case: Splenomegaly and Atypical Lymphocytes
Oncohematology clinical case: patient with splenomegaly, leukocytosis, and atypical lymphocytes in blood smear, BRAF mutation negative. Choose diagnosis.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Lab test interpretation
Elevated ALT, AST, and GGT: Differential Diagnosis
Clinical case review: isolated elevation of ALT, AST, and gamma-GT in a 36-year-old woman. Calculation of de Ritis ratio, search for causes, and examination plan.
Hematology
Elevated MCHC in Blood Test: Causes and Algorithm
What to do if MCHC is elevated above 375 g/L in CBC: causes of false elevation, cold agglutination, sample warming, and blood smear evaluation.
Hematology
Monocyte Morphology in Peripheral Blood Smears
Explore the morphological features of monocytes and lymphocytes in peripheral blood smears. Learn about leukocyte microscopy in laboratory diagnostics.
Hematology
Erythrocyte Morphology: Poikilocytosis and Anisocytosis Types
An illustrated atlas of erythrocyte morphology: main forms of poikilocytes and variants of anisocytosis in peripheral blood smear microscopy.
Parasitology
Anaplasmosis: Anaplasma phagocytophilum Morulae in Blood Smear
A clinical case of granulocytic anaplasmosis: Anaplasma phagocytophilum morulae found in neutrophils on a blood smear, along with thrombocytopenia and hyponatremia.
Hematology
Hemosiderin in Urine in Paroxysmal Nocturnal Hemoglobinuria
Urine sediment in paroxysmal nocturnal hemoglobinuria: microscopy of hemosiderin clumps in epithelial cells and a hyaline cast during hemolysis.
Lab test interpretation
Elevated Amylase: Causes and Diagnostic Algorithm
Exploring non-pancreatic hyperamylasemia, the role of salivary gland involvement and macroamylasemia, and a clinical algorithm for patient evaluation.
Clinical cases
Rh Factor and Antibody Misidentification in Transfusion
A clinical case detailing severe consequences of Rh factor and anti-erythrocyte antibody misidentification before blood transfusion, and legal liability.
Hemostasis
Differential Diagnosis of Thrombocytosis in Complete Blood Count
What to do when thrombocytosis exceeds 450,000/µL: common causes of reactive platelet elevation, the role of ferritin and CRP, and indications for genetic tests.
Hematology
Morphology of Large Granular Lymphocytes in Blood Smear
Morphological features of large granular lymphocytes (LGL) in peripheral blood: cytoplasm with azurophilic granularity on microscopy.
Hematology
Eosinophilic Myelocytes: Cytomorphology in Blood Smears
Morphological features of eosinophilic myelocytes in blood smears: specific orange-pink granularity, nuclear shape, and cytoplasm.