Hematology
Normoblastosis in CBC: Counting and Morphology
Assessment of normoblastosis in CBC: over 100 normoblasts per 100 leukocytes, hematology analyzer scattergram, and blood smear morphology in anemia.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Hematology
Pappenheimer Bodies in Hemolytic Anemia Blood Smear
A case of hereditary hemolytic anemia in an 18-year-old male: microcytosis, hypochromia, Pappenheimer bodies in erythrocytes, and analyzer parameters.
Hematology
Iron Deficiency Anemia Therapy: Dosing Frequency
Clinical guidelines for iron deficiency anemia therapy: advantages of alternating regimens and low-dose iron preparations over frequent administration.
Oncohematology
Acute Monocytic Leukemia: Morphology and Diagnostic Criteria
A clinical case of acute monocytic leukemia: hyperleukocytosis, monoblast and promonocyte morphology in blood smear, immunophenotyping, and WHO criteria.
Hematology
Stomatocytosis: Erythrocyte Morphology and Causes
What is stomatocytosis, how do stomatocytes appear in a blood smear, and in which hereditary and acquired pathologies are they found?
Lab test interpretation
Diuretic-Induced Hyperkalemia: A Clinical Case Study
Analysis of an iatrogenic hyperkalemia case: potassium levels rose to 6.7 mmol/L due to concurrent spironolactone and potassium supplement intake.
Oncohematology
Acute Promyelocytic Leukemia: Blood Smear and Analyzer
Laboratory signs of acute promyelocytic leukemia: cytopenia on a hematology analyzer and morphology of atypical promyelocytes in a blood smear.
Hematology
Artifacts and Inclusions in Lymphocyte Cytoplasm
How to distinguish true cytoplasmic inclusions from fixation and staining artifacts in a blood smear: morphological features and differential diagnosis.
Laboratory methods
Blood Smear Artifacts from Underfilled EDTA Tubes
How excess EDTA in small blood volumes distorts analyzer scattergrams and cell morphology: echinocytes, nuclear pyknosis, and endothelial aggregates.
Education
Infectious Exanthems in Children: Differential Diagnosis
Differential diagnosis of infectious exanthems in children: clinical examples of Lyme disease, herpes, roseola, ecthyma gangrenosum, and streptoderma.
Hematology
Severe Iron Deficiency Anemia with Hemoglobin 18 g/L
A clinical case of critical iron deficiency anemia: hematological parameters, erythrocyte morphology in a blood smear, and biochemical markers.
Oncohematology
Langerhans Cell Histiocytosis in Bone Marrow
Morphology of Langerhans cells in bone marrow aspirate, clinical manifestations, immunophenotype (CD1a, langerin), and diagnostic criteria for histiocytosis.