Oncohematology
Normoblastosis and Dyserythropoiesis in MDS Blood Smear
A clinical case of MDS in a 53-year-old woman: 180 normoblasts per 100 leukocytes in CBC, dyserythropoiesis, 4% blasts, and giant platelets in the smear.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Oncohematology
Acute Promyelocytic Leukemia: Blood & Bone Marrow Smears
A 73-year-old female patient with suspected acute promyelocytic leukemia: hemogram parameters, atypical promyelocytes in blood and bone marrow.
Lab test interpretation
Interpreting Immunograms by Flow Cytometry
A clinical example of an immunogram using a flow cytometer: evaluating activated CD3+HLA-DR+ T-lymphocytes and NK cells in inflammatory processes.
Oncohematology
Pancytopenia and Blasts Post-Chemotherapy: A Case Study
A case of pancytopenia with blasts and myelocytes after sarcoma chemotherapy: why bone marrow aspiration is essential over peripheral blood immunophenotyping.
Oncohematology
Leukemia Cutis: Specific Skin Lesions in Leukemia
Leukemia cutis is the infiltration of the skin by blast cells in acute myeloid leukemia. Clinical variants of skin manifestations include papules, plaques, nodules, and ulcers.
Hematology
Major Beta-Thalassemia: External Signs and Symptoms
External manifestations of major beta-thalassemia: facial bone deformities, cutaneous hemosiderosis in severe hemolytic anemia and iron overload.
Hematology
Cold Agglutinin Disease: Symptoms and Diagnosis
Cold agglutinin disease: mechanism of autoimmune hemolysis by IgM antibodies, symptoms, and features of cold agglutination of erythrocytes in blood tests.
Education
Laboratory Medicine Forum at MONIKI: Standards & Technologies
Join the Laboratory Medicine Forum on November 19 at MONIKI, Moscow, for discussions on standards, service organization, technology exhibition, and CME credits.
Education
Remote Work for Doctors: Online Medical Consultations
Remote work opportunities for doctors of all specialties: written patient consultations in your free time, with medical diploma verification.
Hematology
Koilonychia and Atrophic Glossitis in Iron Deficiency
Clinical signs of sideropenic syndrome in iron deficiency anemia: atrophy of tongue papillae, angular stomatitis, and koilonychia (spoon-shaped nails).
Hemostasis
Rendu-Osler Disease: Telangiectasias and Anemia
Rendu-Osler disease: causes of endothelial insufficiency, skin and mucous membrane telangiectasias, risk of occult GI bleeding and iron deficiency anemia.
Oncohematology
Prolymphocytic Transformation of Chronic Lymphocytic Leukemia
A case of CLL transformation to prolymphocytic leukemia: leukocytosis increased to 162×10⁹/L in 4 months, with up to 40% prolymphocytes in blood smear.