Oncohematology
Pseudopelger-Huët Anomaly of Neutrophils in Blood Smear
Pseudopelgerization of neutrophils as an early marker of myelodysplastic syndrome. Morphology of Pelgeroid cells in blood smear in anemia of unknown origin.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Oncohematology
Bone Marrow Cancer Metastasis: Cellular Morphology
Cytological features of solid cancer metastases in the bone marrow: morphology of atypical non-hematopoietic cells and complexes in a 60-year-old man's aspirate.
Education
Christmas Tree from Lab Consumables: A Festive Creation
A unique Christmas tree assembled by clinical diagnostic laboratory staff using plastic bio-material containers and test tube racks, bringing festive cheer.
Hematology
Basophilic Stippling of Erythrocytes in Blood Smear
Erythrocyte morphology in blood smears in anemia: detection of basophilic stippling, its clinical and diagnostic significance, and causes.
Hematology
Neutrophil Hypogranulation: Causes and Morphology
What neutrophil hypogranulation in a blood smear means: diagnostic significance in severe infections and myelodysplastic syndrome (MDS).
Hematology
Blood Chimeras: Erythrocyte Antigen Phenotyping
What are blood chimeras and why do two erythrocyte populations arise? Features of the double field reaction in Rh and Kell system antigen typing.
Hematology
Neutrophil Vacuolization: Causes and Clinical Significance
What neutrophil vacuolization in a blood smear means: a marker of severe bacterial infection, sepsis, or an artifact of prolonged EDTA sample storage.
Oncohematology
Blast vs. Lymphoma Cells: Sysmex WPC Channel Insights
A clinical case demonstrating the differential diagnosis of blasts and atypical lymphocytes in suspected lymphoma using the WPC channel of a Sysmex XN-9100 analyzer.
Hematology
Cabot Rings in Erythrocytes: Morphology and Diagnostics
What are Cabot rings in erythrocytes? Morphological features, causes of appearance in megaloblastic anemia and myelodysplastic syndrome.
Hematology
Emperipolesis in Megakaryocytes: Bone Marrow Cytology
The phenomenon of emperipolesis in bone marrow: active penetration of intact cells into the megakaryocyte cytoplasm in a puncture smear.
Hematology
Toxic Granulation of Neutrophils: Causes and Morphology
What toxic granulation of neutrophils in a blood smear means. Mechanism of granule formation, connection to infection severity, sepsis, and clinical significance.
Hematology
Pelger-Huët Anomaly: Blood Smear Morphology
A clinical case of hereditary Pelger-Huët anomaly. Morphological features of neutrophil nuclear hyposegmentation in peripheral blood.