Oncohematology
Acute Myeloid Leukemia Diagnosis: A Clinical Case Study
A clinical case of acute myeloid leukemia (AML M2) featuring blastemia, hyperleukocytosis, blood smear morphology, and bone marrow immunophenotyping and PCR results.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Oncohematology
Differential Diagnosis of Marked Lymphocytosis
Clinical case of an 84-year-old female patient: leukocytosis 340×10⁹/L, Botkin-Gumprecht shadows, peripheral blood and bone marrow aspirate smears.
Oncohematology
LP Cells in Nodular Lymphocyte-Predominant Hodgkin Lymphoma
Characteristics of LP cells ("popcorn cells") in nodular lymphocyte-predominant Hodgkin lymphoma: cytological features, polylobed nuclei, and immunophenotype CD20+, CD30-.
Hematology
Bacteria in Blood Smear: Contamination or Bacteremia?
How to distinguish bacterial contamination and staining artifacts from true bacteremia during peripheral blood smear microscopy: a case study.
Hematology
Erythrocyte Morphology in Thalassemia and Hemoglobinopathies
Peripheral blood smears in beta-thalassemia, sickle cell anemia, and hemoglobinopathies C and E: HbC crystals, sickle and target cells.
Oncohematology
Acute Monocytic Leukemia M5b: Cell Morphology and Immunophenotyping
A clinical case of secondary acute monocytic leukemia (AML M5b) with hyperleukocytosis of 503×10⁹/L: blood smear morphology and immunophenotyping.
Clinical cases
Borrelia in Peripheral Blood Smear in Lyme Disease
A case report of Borrelia spirochetes found in a blood smear from a patient with fever and thrombocytopenia, illustrating the morphological picture of tick-borne borreliosis (Lyme disease).
Oncohematology
Acute Myeloid Leukemia with inv(16) and Harlequin Cells
A clinical case of acute myeloid leukemia with chromosome 16 inversion. Discovery of Harlequin cells in bone marrow aspirate.
Oncohematology
Pediatric B-Lymphoblastic Leukemia: A Diagnostic Case Study
A clinical case of B-ALL in an an 8-year-old child: leukopenia and anemia without blastemia, bone marrow blastosis, and B-ALL confirmation by flow cytometry.
Laboratory methods
Shubich Method: Granulocyte Cationic Protein Detection
The principle of Shubich's cytochemical reaction with bromophenol blue: detecting cationic lysosomal proteins as granules in the cytoplasm of blood neutrophils.
Oncohematology
Gaucher-like Cells in Bone Marrow Smear in CML
Morphology of Gaucher-like cells in a bone marrow smear from a patient with chronic myeloid leukemia (CML). Differential diagnosis and cytology.
Oncohematology
Chronic Myeloid Leukemia: Peripheral Blood Morphology
A clinical case of CML detected during a routine blood test: hyperleukocytosis 203×10⁹/L, thrombocytosis, granulocyte maturation stages, and BCR-ABL1 mutation.