
Erythroblastic Islands in Bone Marrow Smears
Morphology of erythroblastic islands in bone marrow smears: structure of erythroid rosettes around a macrophage, differentiation of erythroid cells.
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.

Morphology of erythroblastic islands in bone marrow smears: structure of erythroid rosettes around a macrophage, differentiation of erythroid cells.

A clinical case of systemic mastocytosis: splenomegaly, urticaria pigmentosa, blood tryptase level >200 µg/L, and atypical mast cells in the bone marrow.

A clinical case of Hodgkin lymphoma: cytology of a lymph node biopsy, Reed-Sternberg cells, neutrophilic leukocytosis, and microcytic anemia.

A clinical case of acute erythroid leukemia: pancytopenia, blast cells in the smear, erythroid dysplasia, and flow cytometry (CD71+, CD235a+).

A clinical case of CLL with marked leukocytosis (562×10⁹/L): prolymphocyte morphology in a blood smear and immunophenotyping data.

A clinical case of CLL: hyperleukocytosis 117×10⁹/L, thrombocytopenia, absolute lymphocytosis, and Botkin-Gumprecht shadows in peripheral blood.

A clinical case of thrombotic thrombocytopenic purpura: schistocytes in a blood smear, hemolysis, thrombocytopenia, and ADAMTS-13 deficiency.

A clinical case of pertussis in a 2-year-old child: pronounced lymphocytosis, lymphocytes with cleaved nuclei, and smudge cells in the blood smear.

A clinical case of infectious mononucleosis in a 7-year-old child: complete blood count parameters and morphology of reactive lymphocytes in a blood smear.

Analysis of a child's complete blood count: moderate absolute neutropenia and hypereosinophilia, mistakenly considered normal for age by doctors.

A clinical case of large cell neuroendocrine carcinoma metastasis to the bone marrow: cytology of trephine biopsy imprints in pancytopenia.

How blood platelets are formed: a diagram of megakaryocyte cytoplasm fragmentation and phagocytosis of its residual nucleus by bone marrow macrophages.