
Vitamin B12 Deficiency Anemia: Blood and Bone Marrow
A clinical case of vitamin B12 deficiency anemia: macrocytosis (MCV 118 fL), Howell-Jolly bodies, neutrophil hypersegmentation, and megaloblastic erythropoiesis in the bone marrow.
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.

A clinical case of vitamin B12 deficiency anemia: macrocytosis (MCV 118 fL), Howell-Jolly bodies, neutrophil hypersegmentation, and megaloblastic erythropoiesis in the bone marrow.

A clinical case of eosinopenia in acute infection: causes of decreased eosinophils in the blood and the diagnostic value of the indicator as a marker of inflammation.

Morphology of prolymphocytes in peripheral blood with Romanowsky staining: differential diagnosis with lymphocytes and blasts in blood smears.

A clinical case of leukocytosis (35.3×10⁹/L) with anemia and 66.5% monocytosis: morphological evaluation of suspicious mononuclear cells and blasts in a peripheral blood smear.

A 19-year-old patient with infectious mononucleosis: leukocytosis, analyzer scattergram, and reactive lymphocyte morphology in a blood smear.

A clinical case of acute leukemia onset in a 30-year-old female patient: dynamics of complete blood count from neutropenia to 61% blasts in the blood smear.

Assessment of normoblastosis in CBC: over 100 normoblasts per 100 leukocytes, hematology analyzer scattergram, and blood smear morphology in anemia.

A case of hereditary hemolytic anemia in an 18-year-old male: microcytosis, hypochromia, Pappenheimer bodies in erythrocytes, and analyzer parameters.

How to distinguish true cytoplasmic inclusions from fixation and staining artifacts in a blood smear: morphological features and differential diagnosis.

How excess EDTA in small blood volumes distorts analyzer scattergrams and cell morphology: echinocytes, nuclear pyknosis, and endothelial aggregates.

A clinical case review of anemia due to folic acid and vitamin D deficiency in a breastfeeding woman. Evaluation of complete blood count and biochemistry.

A clinical case of solid tumor metastasis to the bone marrow in a patient suspected of acute hemoblastosis: myelogram analysis and cell morphology.