Hematology
Megaloblastic Hematopoiesis in Bone Marrow
Clinical case: morphological signs of megaloblastic erythropoiesis, giant neutrophils, and nuclear hypersegmentation in a bone marrow smear.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Oncohematology
IHC Diagnosis of Hodgkin Lymphoma: CD30, CD15, and PAX5
Immunohistochemical study of a lymph node suspected of Hodgkin lymphoma: evaluation of CD30, CD15, PAX5 markers and histological picture.
Hematology
Unusual Erythrocyte Morphology Artifacts in Blood Smears
Erythrocyte morphology and artifacts in peripheral blood smears: evaluating cell shape, causes of artifactual clearings and fixation defects.
Hematology
Cold Agglutination of Erythrocytes in Complete Blood Count
Impact of cold agglutination on CBC parameters: falsely elevated MCHC, spurious erythrocytopenia, and correction by warming to 37 °C.
Clinical cases
Thymus Hypoplasia and Aplasia in Children: Ultrasound Data
Analysis of a pediatric thymus ultrasound protocol: decreased thymic index, suspected aplasia, and ectopic thymus.
Oncohematology
Megakaryocyte Nuclear Fragments in Chronic Myeloid Leukemia
Detection of megakaryocyte nuclear fragments in peripheral blood smears in chronic myeloid leukemia. Morphological features and microscopy.
Oncohematology
Acute Leukemia: Blood Count Dynamics and Blasts in Smear
A clinical case of acute leukemia manifestation: transformation from leukopenia to leukocytosis with the appearance of blasts in peripheral blood over a month.
Hematology
Assessing Hemoglobin and Hematocrit in Blood Loss
Why hemoglobin and hematocrit levels don't always reflect acute blood loss severity: clinical parameter assessment and risks of unjustified blood transfusion.
Hematology
Complete Blood Count in ARVI: Causes of Leukopenia
Analysis of a complete blood count in a patient with ARVI: moderate leukopenia, relative monocytosis, and clinical interpretation of the leukocyte differential.
Oncohematology
Normoblastosis and Dyserythropoiesis in MDS Blood Smear
A clinical case of MDS in a 53-year-old woman: 180 normoblasts per 100 leukocytes in CBC, dyserythropoiesis, 4% blasts, and giant platelets in the smear.
Oncohematology
Acute Promyelocytic Leukemia: Blood & Bone Marrow Smears
A 73-year-old female patient with suspected acute promyelocytic leukemia: hemogram parameters, atypical promyelocytes in blood and bone marrow.
Lab test interpretation
Interpreting Immunograms by Flow Cytometry
A clinical example of an immunogram using a flow cytometer: evaluating activated CD3+HLA-DR+ T-lymphocytes and NK cells in inflammatory processes.