
AML with t(8;21) Translocation: Morphology and Genetics
Diagnostic criteria and morphological features of AML with t(8;21) translocation: blast assessment, granulocyte anomalies, and differential diagnosis with APL.
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.

Diagnostic criteria and morphological features of AML with t(8;21) translocation: blast assessment, granulocyte anomalies, and differential diagnosis with APL.

Morphological features of atypical mononuclear cells (virocytes) in blood smears: nuclear polymorphism, cytoplasmic basophilia, and infection diagnosis.

Morphological features of blasts in blood: high nuclear-cytoplasmic ratio, delicate chromatin, and the role of immunophenotyping in diagnosis.

Clinical case: atypical mononuclear cells (32%) and leukocytosis 21.38×10⁹/L in a 23-year-old female patient. Sysmex WDF and WPC scattergrams, cytology, and leukocyte differential.

Morphological features of blasts in acute lymphoblastic leukemia L3 (FAB) and Burkitt lymphoma: cytoplasmic basophilia, pronounced cell vacuolization.

Clinical case of CML: 7% blasts, myelocytes, and metamyelocytes in CBC. Cell morphology and the importance of blast count in myeloid leukemia.

Clinical case of acute myeloid leukemia in a 15-year-old teenager: Auer rods in blasts, pancytopenia, leukocytosis, and analyzer scattergram.

Clinical case analyzing blast morphology in a blood smear: identifying deep clefts, nuclear lobulation, binuclearity, and chromatin structure assessment.

Detection of 12% blasts in leukopenia and severe thrombocytopenia. Features of blood smear microscopy and analyzer scattergram in pancytopenia.

A clinical case of leukemia in a 63-year-old female: leukocytosis, 73% blasts, and the value of reticulated platelet analysis for early diagnosis.

A clinical case of acute erythroid leukemia (AML M6): blasts and severe dyserythropoiesis in bone marrow, cytochemical glycogen study.

A clinical case of acute promyelocytic leukemia (AML M3) diagnosis, including blood and bone marrow cell morphology, cytochemistry (MPO, PAS), and PML/RARa translocation detection.