Hematology
Platelet Dysplasia Mimicking Trypanosomiasis
A case of severe platelet dysplasia in a 66-year-old patient. Morphology of atypical platelets in blood smear, analyzer histograms, and resemblance to trypanosomiasis.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Laboratory methods
Formalin in the Lab: Toxicity and Safety Guidelines
Why formalin is indispensable for tissue fixation, the dangers of formaldehyde vapor, and how to ensure safety when working with and spilling the reagent in the lab.
Parasitology
Parasitology Case: Identifying Helminth Eggs in Stool
A diagnostic parasitology exercise: identify the helminth species from a microphotograph of an egg in stool, considering migratory and intestinal phases of invasion.
Lab test interpretation
Polyomavirus in Urine: Cytological Cell Types and Cancer Risk
Morphological cell types in polyomavirus infection in urine sediment: differential diagnosis of benign changes and urothelial carcinoma.
Hematology
Cervical HSIL and SCC: Cytological Diagnosis
A clinical case of cytological examination of a cervical smear from a 46-year-old woman diagnosed with HSIL, with suspicion of squamous cell carcinoma (SCC).
Hemostasis
Macrotrombocytes in Blood Smear with Thrombocytopenia
A case study of macrotrombocytes in an adolescent: comparing platelet counts by Fonio and hematology analyzer in thrombocytopenia.
Oncohematology
Cytoplasmic Clasmatosis in Chronic Lymphocytic Leukemia
Morphological features of B-CLL: the phenomenon of cytoplasmic clasmatosis of tumor lymphocytes in a blood smear and immunophenotyping data of a monoclonal population.
Clinical cases
Cervical Liquid-Based Cytology Case Study: ThinPrep
A clinical case in gynecological cytology: identify epithelial changes in a 44-year-old woman's ThinPrep slide based on the provided micrograph.
Oncohematology
Canine Hemophagocytic Histiocytic Sarcoma: Cytology
Clinical case of canine hemophagocytic histiocytic sarcoma: cytology of lymph node and bone marrow, erythrophagocytosis, anemia, and thrombocytopenia.
Clinical cases
Cytological Features of Medullary Thyroid Carcinoma
A clinical case of medullary thyroid carcinoma in a 70-year-old female patient: cytological features of the aspirate, cellular polymorphism, and microscopy.
Lab test interpretation
Amyloid Bodies in Ejaculate During Sperm Microscopy
Features of microscopic detection of amyloid bodies in native ejaculate smears. Diagnostic significance in spermogram microscopy.
Clinical cases
Cytological Diagnosis of Phaeohyphomycotic Cyst
A clinical case of a phaeohyphomycotic cyst of the thigh caused by Medicopsis romeroi: fine-needle aspiration, cytology, and PAS and GMS staining.