Hematology
Ring-shaped Leukocyte Nuclei in Peripheral Blood Smears
Holes and ring-shaped nuclei in leukocytes: morphological features of reactive lymphocytes in EBV, granulocyte dysplasia, and differential diagnostics.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Clinical cases
Adenocarcinoma Signet Ring Cells in Pleural Fluid
Cytological findings of metastatic gastric adenocarcinoma in pleural fluid: identification of signet ring cells with Papanicolaou stain.
Lab test interpretation
Triple Phosphate Crystals in Stool: Coprogram Microscopy
Detection of triple phosphate (struvite) crystals during stool microscopy: crystal morphology in coprogram and clinical-diagnostic significance.
Oncohematology
Acute Myeloid Leukemia: Blasts and Auer Rods in Blood
A clinical case of acute leukemia: hyperleukocytosis 181×10⁹/L, 97% blasts in the blood smear, Auer rods, and hematology analyzer scattergrams.
Oncohematology
Dendritic Cell Neoplasm: Bone Marrow Cell Morphology
A clinical case of agranulocytosis in a young female patient: cytopenic syndrome and atypical blast cells in a bone marrow smear, with suspicion of BPDCN.
Clinical cases
Herpes Simplex Virus Cytopathic Effect in a Vaginal Smear
Multinucleated giant cells resembling mulberry cells in a vaginal smear: herpes simplex virus cytopathic effect observed via methylene blue microscopy.
Hematology
Cabot Rings in Erythrocytes: Morphology and Diagnostics
Learn about Cabot rings in erythrocytes: their nature, diagnostic significance in megaloblastic anemia, and erythropoiesis disorders. Cytology of blood smears.
Oncohematology
Blast Morphology: The Mercedes-Benz Sign in Acute Leukemia
Microscopic features of blast cells in leukemia: phenomena of mutual cytoplasm and nuclear deformation, contact groups of blasts in peripheral blood smears.
Oncohematology
Hairy Cell Leukemia Suspected in Hyperleukocytosis
A clinical case of severe leukocytosis up to 300 × 10⁹/L with absolute lymphocytosis. Cell morphology with cytoplasmic projections and recommendation for immunophenotyping.
Lab test interpretation
Spermiophages in Ejaculate Smear: Macrophage Morphology
Morphology of spermiophages in a stained ejaculate smear during spermogram. Phagocytosis of spermatozoa by macrophages and their clinical and diagnostic significance.
Parasitology
Trichinellosis: Morphology of Trichinella Nematode Larvae
The causative agent of trichinellosis: Trichinella nematode life cycle, migration and encapsulation of larvae in striated muscles, microscopic features.
Oncohematology
Hairy Cell Leukemia in Peripheral Blood Smear
A clinical case of hairy cell leukemia in a 55-year-old man with significant leukocytosis. Morphology of hairy cells in a blood smear.