
Football-Ball Chromatin in Chronic Lymphocytic Leukemia
Characteristic clumped nuclear chromatin structure of lymphocytes, resembling a football, in a blood smear from chronic lymphocytic leukemia (CLL).
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.

Characteristic clumped nuclear chromatin structure of lymphocytes, resembling a football, in a blood smear from chronic lymphocytic leukemia (CLL).

A case of Myxosporidia (presumed Henneguya salminicola) found in omul muscle: macroscopic view of cysts and microscopic examination of parasite spores.

Morphological criteria for erythroid dysplasia in myelodysplastic syndrome: multinuclearity, pyknosis, nuclear budding, and basophilic stippling.

Microscopic features of parasites in stool and blood: eggs of Schistosoma, Ascaris, pinworms, hookworms, dwarf tapeworms, Giardia cysts, and trypanosomes.

Microscopy of urine sediment in massive hematuria: an entire field of view covered with unchanged (fresh) erythrocytes in a patient with a bladder tumor.

Detection of methotrexate crystals in urine sediment with acute kidney injury after high-dose therapy. Features of sediment microscopy.

Analysis of a case involving a false-positive HIV PCR test result caused by amplicon contamination. Exploring the reasons for zoning violations in a PCR laboratory.

Microscopy of native prostatic secretion: morphology of amyloid bodies, mucus, and cellular elements at 40x magnification. A guide for laboratory hematology.

Learn about Schistosoma mekongi: egg morphology with a short lateral spine, stool microscopy, and differential diagnosis from Schistosoma japonicum.

Key morphological features of blast cells in peripheral blood smears in acute leukemia: evaluating nuclear chromatin and cytoplasm structure.

Morphology of sulfadiazine crystals in urine sediment during acute kidney injury: bright-field and polarized light microscopy of a native preparation.

Cytological features of cryptococcal thyroiditis in a thyroid aspirate: follicular epithelium, lymphocytes, and histiocytes with cryptococci.