Morphology of Auer rods in myeloblasts in AML: mechanism of formation from abnormal primary granules and cytological features of blasts.
On a cytological preparation from a patient with acute myeloid leukemia, a large number of Auer rods were observed in blast cells. In one of the blasts, the stage of Auer rod formation was captured.
Auer rods are formed as a result of the fusion and aggregation of abnormal primary granules (lysosomes) containing myeloperoxidase and other lysosomal enzymes.
🔬 Source: from the archive of Brazilian hematology specialist Marcio Melo
Morphological characteristics and types of blast cells: myeloblasts, monoblasts, erythroblasts, and megakaryoblasts in bone marrow and peripheral blood smears.
Morphology of blast cells with Auer rods on a peripheral blood smear in acute myeloid leukemia. Cytological diagnostic criteria.
Auer rods are crystalline structures in myeloid cells, pathognomonic for acute myeloid leukemia. They form from primary granules.
