Clinical cases

Parakeratosis in Cervical Cytology Smear

Cytological features of parakeratosis in cervical leukoplakia: squamous epithelial cell morphology, NILM criteria, and microscopic characteristics.

🔬Cytology. Cervical smear. Leukoplakia. Educational material from the Department of Clinical Laboratory Diagnostics, RMACPE. ✅ Woman, 34 years old, day 24 of cycle. Squamous epithelium with signs of parakeratosis (NILM).

✅Parakeratosis is a disorder of squamous epithelial cell differentiation, resulting in the presence of cells that are similar in shape to superficial layer cells but are smaller, appearing singly or in sheets. The cytoplasm is dense, sometimes shiny, and stains intensely blue with Pappenheim and Leishman stains.