Clinical cases

Adenocarcinoma Signet Ring Cells in Pleural Fluid

Cytological findings of metastatic gastric adenocarcinoma in pleural fluid: identification of signet ring cells with Papanicolaou stain.

Pleural fluid smear: adenocarcinoma signet ring cells stained with Papanicolaou
Pleural fluid smear: adenocarcinoma signet ring cells stained with Papanicolaou

🔬 Numerous isolated cells with signet ring deformation, characteristic of adenocarcinoma (Papanicolaou stain), were found in the pleural fluid of a patient with gastric cancer.

👉 Source: Cibas - Cytology. Diagnostic Principles and Clinical Correlates 5 ed (2021)

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