Signet Ring Cells in Pleural Fluid Smear: A Case Study

Cytological examination of pleural fluid reveals signet ring cells, characteristic of adenocarcinoma. Romanowsky-Giemsa stain used.

Karina Bikashyeva 1 min April 22, 2026

Pleural fluid smear: signet ring cell with nucleus displaced to the periphery

Pleural fluid smear: large signet ring cell in the center of the field of view

Pleural fluid smear: vacuolated signet ring-shaped cell

In the pleural fluid smear, signet ring cells are present. The patient has a diagnosis of chronic cerebral ischemia. Stained with Romanowsky-Giemsa.

🙏 The publication was kindly provided by biologist Karina Bikasheva, Luhansk People’s Republic.

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