Laboratory methods

Slide Substitution and Sample Labeling in Cytology

Analysis of a case involving slide substitution during biopsy examination, the consequences of a false diagnosis, and methods to reduce the risk of sample mix-ups in the laboratory.

Thematic illustration with the inscription Error in Laboratory No. 10
Thematic illustration with the inscription Error in Laboratory No. 10

Rubric Error in the Cytology Laboratory Slide Substitution During Biopsy Examination In one pathomorphology center, a laboratory assistant accidentally mixed up the labeling of microscope slides. As a result, the patient received a false-positive diagnosis of “malignant tumor.” She underwent unnecessary surgical intervention before the error was discovered during a second consultation at another institution. ❓ How can the risk of sample substitution be reduced in cytological/histological practice?

🙏 Project “Repentance”. This is a special section where everyone can anonymously confess their laboratory error. For this, we have created a special Google form that you can fill out without providing your name.