Lab test interpretation

Polyomavirus in Urine Cytology: Cell Types and Cancer Risk

Cytological diagnosis of polyomavirus in urine: the significance of morphological cell types A, B, C, and D in assessing the risk of bladder cancer.

Urine cytological smear: morphotypes A, B, C, and D of cells with polyomavirus
Urine cytological smear: morphotypes A, B, C, and D of cells with polyomavirus

🔬 Polyomavirus in urine: when should you be concerned? 🚨

A new study 🧐 has revealed important details about the diagnosis of polyomavirus (PV) in urine tests and its connection to bladder cancer. Here’s the main takeaway:

  • 🦠 Type A (“classic PV”) — almost always benign, even if other suspicious cells are present.
  • 🕸️ Type B (“spiderweb chromatin”) — in 22% of cases, this may be cancer.
  • ⚡ Type D (severely altered cells) — in 61.5% of cases, it is associated with a high risk of tumor.

Conclusions: 🔹 If type A cells are present in the analysis, the risk of cancer is extremely low (1.2%) — no need to worry. 🔹 Types B, C, and D cells without type A — a reason for additional studies, especially in patients with a history of cancer.

📌 Source: Li Y. et al. Diagnostic Cytopathology, 2025.

Medicine Urology Diagnostics ScienceJustVK DOWNLOAD PDF