Hematology
Clinical Symptoms of Anemia: Missing Signs
Exploring the clinical manifestations and symptoms of anemic syndrome: identifying signs of hypoxia and sideropenia not included in the provided diagram.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Hematology
Folic Acid Deficiency and Anemia During Lactation
A clinical case review of anemia due to folic acid and vitamin D deficiency in a breastfeeding woman. Evaluation of complete blood count and biochemistry.
Hematology
Neutrophil Chemotaxis in Necrosis and Inflammation
The role of segmented neutrophils in inflammation and tissue necrosis: mechanisms of chemotaxis, action of pro-inflammatory cytokines, and granulocyte migration.
Hematology
Erythropoietin: Synthesis Regulation and Erythropoiesis Stimulation
Exploring erythropoietin expression regulation via HIF-2α, the shift of synthesis from liver to kidneys, gene variants in erythrocytosis, and anemia therapy.
Oncohematology
Acute Myeloid Leukemia: Blasts and Dyserythropoiesis
Clinical case of acute myeloid leukemia: bone marrow blast morphology and multinucleated erythroblasts as a sign of dyserythropoiesis.
Lab test interpretation
Renal Epithelial Cells with Fatty Degeneration in Urine
Morphology of renal epithelial cells with fatty degeneration in urine sediment: microscopy of native preparation, size and light refraction of lipid droplets.
Lab test interpretation
Coniophages and Alveolar Macrophages in Sputum Microscopy
Morphology of alveolar macrophages (coniophages) in native sputum smears: phagocytosis of coal dust, soot, and pigments during microscopic analysis.
Oncohematology
Laboratory Diagnosis of Acute Leukemia by Blood Smear
Signs of acute leukemia: pronounced hyperleukocytosis on the analyzer, WDF scattergram, and peripheral blood smear microscopy with massive blastemia.
Lab test interpretation
Pleural Fluid Cytology: Breast Cancer Metastasis
Morphology of cell clusters in pleural fluid in breast cancer metastasis: features of spherical cell complexes in effusion cytology.
Oncohematology
Acute Myeloid Leukemia M2: Myelogram in FLT3-ITD
Clinical case of resistant AML (FAB-M2) with FLT3-ITD mutation. Bone marrow morphology: 23% blasts, dyserythropoiesis, micromegakaryocytes.
Hematology
Normoblastosis in CBC: Counting and Morphology
Assessment of normoblastosis in CBC: over 100 normoblasts per 100 leukocytes, hematology analyzer scattergram, and blood smear morphology in anemia.
Oncohematology
Feline Eosinophilic Leukemia: Hyperleukocytosis in Blood Smear
A clinical case of extreme leukocytosis (>370,000/µL) in a cat with suspected eosinophilic leukemia: eosinophil morphology and a mast cell in the smear.