Oncohematology
Multiple Myeloma: Bone Marrow Morphology
A clinical case of multiple myeloma in a 65-year-old patient: bone marrow infiltration by atypical plasma cells up to 56%, cytoplasmic clasmatosis, and anemia.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Hematology
Megaloblastic Anemia in a Child: Cabot Rings in Blood Smear
Clinical case of anemia in a 1.5-year-old child: Cabot rings, pronounced basophilic stippling of erythrocytes, and macrocytosis in peripheral blood.
Hematology
Barr Bodies in Neutrophils: Identifying Sex Chromatin
Morphological identification of Barr bodies (sex chromatin) in peripheral blood neutrophils: a clinical case of a female patient in the intensive care unit.
Education
Clinical Laboratory Diagnostics: A Day in the Life
A look into the daily work of clinical diagnostic laboratory specialists: smear microscopy, automated hematology analyzers, and lab workstation organization.
Oncohematology
Blast Morphology: The Mercedes-Benz Sign in Acute Leukemia
Microscopic features of blast cells in leukemia: phenomena of mutual cytoplasm and nuclear deformation, contact groups of blasts in peripheral blood smears.
Lab test interpretation
Hemosiderin in Urine Sediment: Microscopy and Perls' Reaction
Hemosiderin in urine sediment as a marker of intravascular hemolysis. Mechanism of hemosiderinuria formation, sediment microscopy, and cytochemical Perls' reaction.
Education
Christmas Tree from Lab Consumables: A Festive Creation
A unique Christmas tree assembled by clinical diagnostic laboratory staff using plastic bio-material containers and test tube racks, bringing festive cheer.
Hematology
Howell-Jolly Bodies in Blood Smear: Morphology and Causes
What are Howell-Jolly bodies in erythrocytes? Learn about the mechanism of nuclear remnant formation and their causes in megaloblastic anemia, hemolysis, and asplenia in blood smears.
Lab test interpretation
Macrophages in Urine Sediment with Hemolytic Anemia
A clinical case of macrophages found in the urine sediment of a child with hemolytic anemia. Microscopy of native preparation and erythrocyte detritus.
Laboratory methods
Blood Smear Artifacts from Underfilled EDTA Tubes
How excess EDTA in small blood volumes distorts analyzer scattergrams and cell morphology: echinocytes, nuclear pyknosis, and endothelial aggregates.
Lab test interpretation
Ammonium Urate and Calcium Oxalate Crystals in Urine
Urine sediment microscopy: identification of ammonium urate crystals ("thorn apple"), calcium oxalates, and associated bacteriuria.
Clinical cases
Leptothrix in Vaginal Smear: Microscopic Features
Microscopic features of genitourinary tract smears: differential diagnosis of Leptothrix bacteria, concomitant microflora, and artifacts.