
Niemann-Pick Disease: Storage Cells in Bone Marrow
A clinical case of Niemann-Pick disease in a 4-year-old child: morphology of foamy storage cells in a bone marrow aspirate smear.
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.

A clinical case of Niemann-Pick disease in a 4-year-old child: morphology of foamy storage cells in a bone marrow aspirate smear.

An illustrated atlas of erythrocyte morphology: main forms of poikilocytes and variants of anisocytosis in peripheral blood smear microscopy.

A diagnostic challenge in laboratory parasitology: microscopy of a 95 µm finding. Clinical clues and morphological features provided.

A clinical case of acute promyelocytic leukemia: pancytopenia, blasts, CD34- and HLA-DR- immunophenotype, myeloperoxidase cytochemistry, and management strategy.

Clinical case: mutilating osteoarthropathy and 30% plasmacytosis in the bone marrow of a 12-year-old child. Morphology of plasma cells, Mott cells, and Russell bodies.

Morphological assessment of erythrocytes in peripheral blood smears: signs of normochromia, hypochromia, and hyperchromia in the differential diagnosis of anemias.

Morphology of blasts in a peripheral blood smear from a patient with acute myeloid leukemia (AML) undergoing therapy: leukopenia and 21% blast cells.

Gaucher cells found in the bone marrow of a 2-year-old child with splenomegaly, thrombocytopenia, and anemia. Morphological features and clinical picture.

Morphology and clinical significance of granular casts in urine sediment. Causes of formation, differential diagnosis in renal pathology.

Cytological examination of bone marrow in a child with Burkitt's lymphoma: differential diagnosis of osteoclasts, osteoblasts, and tumor cells.

Case study of suspected MDS in an 86-year-old patient: pseudo-Pelger-Huët anomaly of neutrophil nuclei, macrocytic anemia, thrombocytopenia, and analyzer data.

What polychromatophilia of erythrocytes in a blood smear means: causes of polychromatophils, connection with reticulocytosis and enhanced erythropoiesis.