Oncohematology
Acute Promyelocytic Leukemia: Morphology and Genetics
A clinical case of acute promyelocytic leukemia in a 34-year-old male: atypical promyelocytes in the smear, t(15;17) translocation, and analyzer parameters.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Lab test interpretation
Erythrocyte Casts in Urine Sediment Microscopy
Morphology of erythrocyte casts in urine sediment: microscopic signs of renal hematuria in glomerulonephritis and other kidney lesions.
Hematology
Neutrophil Hypersegmentation: Causes and a Clinical Case
A clinical case of hypersegmented neutrophils in a patient with essential thrombocythemia, high MCV, and acute bronchitis.
Hematology
Basophils and IgE in Allergic Reactions: A Hematology School Overview
Explore the mechanism of basophil activation in IgE-mediated allergic reactions and anaphylaxis, focusing on receptor interactions and granulocyte degranulation.
Lab test interpretation
Charcot-Leyden Crystals in Sputum: A Microscopic Case Study
A clinical case detailing the detection of Charcot-Leyden crystals in the sputum of a patient with COPD and pneumonia. Microscopic findings of a native preparation.
Parasitology
Bile Microscopy: Opisthorchis Felineus Eggs
Microscopic findings in bile during opisthorchiasis: detection of Opisthorchis felineus eggs in a native preparation during duodenal content examination.
Oncohematology
Blast Morphology in Myelodysplastic Syndromes
Learn about the morphological features of blast cells in peripheral blood in myelodysplastic syndromes (MDS): smear microscopy and differential diagnosis.
Parasitology
Antiparasitic Immunity: Role of Eosinophils and IgE
Mechanisms of antiparasitic immune response: role of Th2 lymphocytes, IgE secretion, and activation of eosinophils with release of cytotoxic granule proteins.
Oncohematology
Sézary Syndrome: Atypical Lymphocytes in Blood Smear
A clinical case of Sézary syndrome: erythroderma, leukocytosis, and lymphoid cells with characteristic cerebriform nuclei in a blood smear.
Hematology
Hematology Exercise: Reactive Lymphocytes in Blood Smear
A practical exercise in leukocyte morphology: identify which numbered cell in the peripheral blood smear is not a reactive lymphocyte.
Oncohematology
Acute Myeloid Leukemia with Antecedent Myelodysplastic Syndrome
Bone marrow findings in AML with antecedent MDS: 19.8% blasts, 68% erythroid hyperplasia, dyserythropoiesis, macrophages, and pancytopenia.
Lab test interpretation
Renal Epithelial Fatty Degeneration in Urine Sediment
Morphology of renal epithelium with fatty degeneration: microscopy of urine sediment in native form and after Sudan III staining at 400x magnification.