Hematology
Neutrophil Vacuolization: Causes and Clinical Significance
What neutrophil vacuolization in a blood smear means: a marker of severe bacterial infection, sepsis, or an artifact of prolonged EDTA sample storage.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Oncohematology
Acute Myeloid Leukemia: Blasts in Pleural Fluid
A clinical case of recurrent acute myeloid leukemia: detection of blasts in pleural fluid using cytocentrifugation and flow cytometry.
Hematology
Dyserythropoiesis: Atypical Normoblast in Blood Smear
Morphological features of nucleated erythroid cells: an example of a normoblast with a lobulated nucleus in a digital blood smear with signs of dyserythropoiesis.
Hematology
Lymphocyte Morphology in Blood Smear: Hematology Exercise
A clinical laboratory hematology exercise: identify the condition not characteristic of the presented lymphocyte morphology in peripheral blood.
Hematology
Silicone Lymphadenitis: Lymph Node Puncture Cytology
Cytological signs of silicone lymphadenitis: accumulation of macrophages with numerous optically empty vacuoles in a lymph node aspirate.
Oncohematology
Microscopy Exercise: Identifying Cells in a Blood Smear
A clinical question on peripheral blood smear microscopy: help identify leukocyte morphology and perform differential diagnosis of pathology.
Oncohematology
Myelodysplastic Syndrome: Bone Marrow Morphology
Clinical case of suspected MDS: dyserythropoiesis, 10% blasts in bone marrow, cytopenia, and normoblasts in peripheral blood.
Hematology
Hereditary Pyropoikilocytosis: Erythrocyte Morphology
Morphological features of erythrocytes in hereditary pyropoikilocytosis: marked poikilocytosis, schistocytosis, and microcytosis in a peripheral blood smear.
Oncohematology
Acute Myelomonocytic Leukemia: Monoblasts and Promonocytes
Morphological features of acute myelomonocytic leukemia (AML M4): diagnostic criteria for differentiating monoblasts and promonocytes in a blood smear.
Oncohematology
Erythroid Dysplasia: Signs of Dyserythropoiesis in MDS
Morphological criteria for erythroid dysplasia in myelodysplastic syndrome: multinuclearity, pyknosis, nuclear budding, and basophilic stippling.
Parasitology
Lamblia intestinalis Cysts in a Stool Smear
Morphology of Lamblia intestinalis cysts in the stool of a 4-year-old child. Microscopy of a native preparation with Lugol's solution at x400 magnification for giardiasis diagnosis.
Hematology
Clinical Case: Myelogram Interpretation in a 45-Year-Old Patient
Hematology diagnostic exercise: identify the disease based on bone marrow morphology, pruritus, flushing, and splenomegaly in a 45-year-old patient.