Hematology
Neutrophilic Granulocytes and Mitotic Figure in Bone Marrow
Bone marrow aspirate: morphology of granulocytes with enhanced granularity and a cell in mitosis. May-Grünwald-Giemsa stained smear.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Hematology
Severe Iron Deficiency Anemia with Hemoglobin 18 g/L
A clinical case of critical iron deficiency anemia: hematological parameters, erythrocyte morphology in a blood smear, and biochemical markers.
Hematology
Hematology Exercise: Identifying Cells in a Blood Smear
A diagnostic exercise in blood smear microscopy: identify the leukocytes presented in a routine blood test from a patient without specific complaints.
Oncohematology
Acute Myelomonoblastic Leukemia: Blood and Bone Marrow Findings
Clinical case of acute myelomonoblastic leukemia in a 61-year-old male: anemia, monocytosis in blood, and monocytoid blastosis in bone marrow aspirate.
Oncohematology
Bone Marrow Plasmocyte Morphology in Multiple Myeloma
Sternal puncture findings in multiple myeloma: plasmocyte infiltration up to 74%, chromatin atypia, clasmacytosis, and rouleaux formation.
Lab test interpretation
Elevated ALT, AST, and GGT: Differential Diagnosis
Clinical case review: isolated elevation of ALT, AST, and gamma-GT in a 36-year-old woman. Calculation of de Ritis ratio, search for causes, and examination plan.
Hematology
Erythrocyte Morphology in Severe Hyperlipidemia
Peculiarities of erythrocyte morphology in blood smears in pronounced hyperlipidemia with triglyceride levels above 1000 mg/dL: blurred membrane contours.
Lab test interpretation
Green Urine After Propofol: Causes of Discoloration
Why urine turns green after propofol infusion. Mechanism of drug metabolite excretion and differential diagnosis in the clinical diagnostic laboratory.
Oncohematology
Cytochemical Reactions in Acute Leukemia Diagnostics
Summary table of cytochemical reactions in hematology: myeloperoxidase, Sudan Black B, esterases, and PAS reaction for differential diagnosis of leukemias.
Oncohematology
Acute Promyelocytic Leukemia: Promyelocyte Morphology
Morphological features of abnormal promyelocytes in acute promyelocytic leukemia (APL M3): butterfly-wing nuclei and marked hyperleukocytosis.
Lab test interpretation
Amyloid Bodies in Prostate Secretion: Microscopic View
Morphology of amyloid bodies in native prostate gland secretion: concentric layering and clinical significance of the finding during microscopy.
Oncohematology
Mixed-Phenotype Acute Leukemia: Blast Cytomorphology
Morphological features of blasts in mixed-phenotype acute leukemia (MPAL): lymphoblasts and promonocytes in a blood smear according to the 2022 WHO classification.