
Macrocytic Anemia and Neutrophil Hypersegmentation
A clinical case of severe macrocytic anemia: pancytopenia, MCV 121.5 fL, neutrophil hypersegmentation in blood smear, and differential diagnosis with MDS.
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.

A clinical case of severe macrocytic anemia: pancytopenia, MCV 121.5 fL, neutrophil hypersegmentation in blood smear, and differential diagnosis with MDS.

Morphology of reactive perivascular plasma cells in a peripheral blood smear. Wright-Giemsa stain, microscopic features of plasma cell clusters.

A clinical case of acute B-lymphoblastic leukemia with MEF2D::BCL9 rearrangement, mimicking Burkitt lymphoma cell morphology: cytogenetics and phenotype.

Clinical laboratory diagnostics exercise: identify the cells in a peripheral blood smear next to an apoptotic neutrophil. Microscopy practice.

Characteristic clumped nuclear chromatin structure of lymphocytes, resembling a football, in a blood smear from chronic lymphocytic leukemia (CLL).

Morphological features of plasma cells in bone marrow aspirate from an 86-year-old female patient with multiple myeloma: cytological picture and microscopy.

Erythrocyte morphology in pyruvate kinase deficiency: numerous echinocytes with spicules appear in the peripheral blood smear.

A myeloblast with probable Auer rods in a peripheral blood smear from a 77-year-old patient with acute leukemia. Morphological criteria for blast identification.

Clinical case of flora smear microscopy: pronounced epithelial cell vacuolization, possible causes of degenerative changes and inflammation.

Microscopy of urine sediment: detection of uric acid crystals and large conglomerates (microliths). Features of their color, shape, and clinical significance.

A clinical case of urogenital schistosomiasis: detecting Schistosoma haematobium eggs in prostatic secretion and microscopic diagnosis.

Evaluating bone marrow aspirate in multiple myeloma remission: mature plasma cell morphology, absence of atypia, and normal myelogram parameters.