Laboratory methods
Preanalytics of a Flora Smear: Spermatozoa in the Sample
A clear example of gross violation of preparation rules for a flora smear test: spermatozoa found in a female sample. Preanalytical stage errors.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Oncohematology
Blasts in Peripheral Blood Smear of a 2-Year-Old Child
Clinical case of acute leukemia in a 2-year-old girl: 85% blast cells in peripheral blood smear, morphological features of lymphoblasts.
Hematology
Monocyte Morphology and Differential Diagnosis in Blood Smears
Understand monocyte morphology: chromatin and cytoplasm assessment, differential diagnosis from reactive lymphocytes and blasts in blood smears.
Oncohematology
Acute Lymphoblastic Leukemia in a Child: Blasts in Blood Smear
A clinical case of acute lymphoblastic leukemia (ALL) in a 10-year-old child: 66% blasts in a blood smear, cytopenia, and masking as erysipelas.
Oncohematology
Hairy Cell Leukemia: Cell Morphology and CBC Findings
A clinical case of hairy cell leukemia: morphology of hairy lymphocytes in a blood smear, cytopenias, and hematological analyzer data.
Hemostasis
Platelet Satellitism: A Cause of Pseudothrombocytopenia
What is platelet satellitism in a blood smear? The mechanism of platelet adhesion to neutrophils in vitro, and false thrombocytopenia on a hematology analyzer.
Hematology
Algorithm for Differential Diagnosis of Anemia in Children
A step-by-step algorithm for the differential diagnosis of anemia in pediatrics: evaluation of reticulocytes, bone marrow biopsy, Coombs tests, and iron metabolism.
Clinical cases
Melanoma Metastasis to Lymph Node: Cytology
Clinical case of melanoma metastasizing to an inguinal lymph node: cytological features of the aspirate, pronounced cellular pleomorphism and atypia.
Hematology
Cabot Rings in Erythrocytes: Morphology and Diagnostics
Learn about Cabot rings in erythrocytes: their nature, diagnostic significance in megaloblastic anemia, and erythropoiesis disorders. Cytology of blood smears.
Oncohematology
Blast Cells in Blood Smear During Acute Leukemia Relapse
Morphology of blast cells in a peripheral blood smear during acute leukemia relapse in an elderly patient: signs of cytopenia and leukocyte differential features.
Oncohematology
Acute Leukemia in CBC: Blastemia and Cytopenia
A case of acute leukemia: hyperleukocytosis 281.9×10⁹/L, anemia, thrombocytopenia, and 84% blasts. Morphology of blast cells in peripheral blood smear.
Hematology
Cervical HSIL and SCC: Cytological Diagnosis
A clinical case of cytological examination of a cervical smear from a 46-year-old woman diagnosed with HSIL, with suspicion of squamous cell carcinoma (SCC).