Oncohematology
Mantle Cell Lymphoma Cell Morphology in Blood
Learn about the morphological features of mantle cell lymphoma cells in peripheral blood smears: size, chromatin structure, nucleoli, and cytoplasm of CD5+ B-cells.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Oncohematology
Acute Myeloid Leukemia with t(8;21): Morphology and Immunophenotype
A clinical case study of acute leukemia: bone marrow blast cytomorphology, CD19 and CD56 co-expression on immunophenotyping, and suspected t(8;21) translocation.
Laboratory methods
Alpha-Naphthyl Acetate Esterase Activity in Monoblasts
Evaluating alpha-naphthyl acetate esterase activity in bone marrow smears to identify monocytic lineage cells: monoblast and promonocyte morphology.
Oncohematology
Blasts in Blood Smear: Acute Leukemia Relapse Case
Clinical case of acute leukemia relapse: blast cells, normoblasts, and marked poikilocytosis in peripheral blood, with hematology analyzer parameters.
Parasitology
Differential Diagnosis of Helminth Eggs in Stool Samples
A clinical case illustrating the differential diagnosis of helminth eggs and plant artifacts during stool microscopy. Key criteria for parasite identification.
Oncohematology
Blast Morphology in Acute Myelomonoblastic Leukemia
A clinical case of untreated acute myelomonoblastic leukemia: 96% blasts in bone marrow, atypical mitoses, and severe pancytopenia.
Oncohematology
Plasma Cells in Blood Smear in Multiple Myeloma
A clinical case of detecting 6% plasma cells in a complete blood count in myeloma before bone marrow aspiration and a sharp increase in free lambda chains.
Oncohematology
Hodgkin Lymphoma Cytology: Lymph Node Touch Imprint
Cytological features of a lymph node touch imprint in Hodgkin lymphoma (nodular sclerosis): atypical cells with marked cytoplasmic basophilia.
Oncohematology
Plasmablastic Transformation of Myeloma in Lymph Node Imprint
Cytological features of plasmablastic transformation of multiple myeloma in a lymph node imprint: immunoglobulin crystals, plasmablasts, Ki-67 up to 100%.
Oncohematology
Anisocytosis of Platelets and Erythrocytes in Myelofibrosis
Blood morphology features in myelofibrosis: giant platelets, pronounced poikilocytosis and anisocytosis of erythrocytes, and Howell-Jolly bodies in the smear.
Hematology
History of Iron Deficiency Anemia and Chlorosis
How iron deficiency anemia was described in the 16th century: chlorosis, maiden's disease, and the first clinical observations by German physician Johannes Lange.
Hematology
Bone Marrow Morphology: Assessing Cellular Composition
How to evaluate a bone marrow smear without patient history: differentiating hematopoietic lineages, cellularity, and maturation signs of granulocytes and normoblasts.