Oncohematology
Granulocyte Vacuolization and Emperipolesis in Bone Marrow
A clinical case of leukocytosis with neutrophil vacuolization, thrombocytopenia, and emperipolesis in bone marrow in a patient with acute leukemia post-BMT.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Oncohematology
MDS Transformation to AML: Bone Marrow Findings
Clinical case of MDS transforming to AML: 43% blasts, pronounced clasmatosis, signs of dyserythropoiesis, and cytochemical bone marrow results.
Lab test interpretation
Elevated Amylase: Causes and Diagnostic Algorithm
Exploring non-pancreatic hyperamylasemia, the role of salivary gland involvement and macroamylasemia, and a clinical algorithm for patient evaluation.
Hematology
Microscopy Challenge: Identify the Cell in Blood Smear
An interactive laboratory hematology challenge: identify the atypical cell in a peripheral blood smear and test your diagnostic skill.
Hematology
Vitamin B12 Deficiency Anemia and Blue Bone Marrow
A clinical case of severe vitamin B12 deficiency with pancytopenia: blue bone marrow morphology and differential diagnostic errors.
Oncohematology
AML and Plasma Cell Neoplasia Coexistence in Bone Marrow
A clinical case of simultaneous acute myeloid leukemia and plasma cell neoplasia: bone marrow cytomorphology and immunophenotyping.
Laboratory methods
Artificial Intelligence in Bone Marrow Aspirate Analysis
Evaluation of the Scopio X100 HT digital morphology system in bone marrow aspirate analysis: AI vs. manual microscopy comparison.
Laboratory methods
Dicentromeric Chromosome: Definition and Formation Mechanism
What is a dicentric (dic) in cytogenetics? Structural features of a dicentric chromosome with two centromeres and translocation mechanisms.
Parasitology
Trichomonas Vaginalis Morphology in Vaginal Smear Microscopy
Microscopic view of Trichomonas vaginalis in a stained vaginal smear: morphological features of the parasite for laboratory diagnosis of trichomoniasis.
Lab test interpretation
Urothelial Carcinoma: Atypical Cells in Urine Sediment
A clinical case of urothelial carcinoma detected by microscopy of stained urine sediment: atypical transitional epithelium, hematuria, and cytodiagnosis.
Parasitology
Corynosoma strumosum Eggs and Larvae: Microscopic Features
Microscopic characteristics of Corynosoma strumosum eggs and larvae in stool and fish tissues: morphological features of the parasite and human infection routes.
Hematology
Alder-Reilly Anomaly in Mucopolysaccharidosis Type VI
Clinical case of mucopolysaccharidosis type VI: coarse azurophilic granulation of neutrophils and monocytes in a blood smear, arylsulfatase B enzyme deficiency.