Oncohematology
Bone Marrow Plasmacytes in Multiple Myeloma
Morphological features of plasmacytes in a myelogram in multiple myeloma: eccentric nucleus, basophilic cytoplasm, and perinuclear halo.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Clinical cases
Cytology Challenge: Cells in Peritoneal Lavage
A clinical cytology challenge: evaluating the cellular composition of peritoneal lavage fluid from a 63-year-old female patient with a history of cancer. ThinPrep method.
Hematology
Crystals in Megakaryocytes: Morphology and Clinical Case
A rare clinical case of crystals found in megakaryocytes in a bone marrow aspirate of a 2-year-old child with infection and thrombocytopenia.
Hemostasis
EDTA-Dependent Pseudothrombocytopenia in Blood Smear
Mechanism of EDTA-dependent pseudothrombocytopenia and in vitro platelet agglutination: a clinical example of spurious thrombocytopenia in blood smear microscopy.
Oncohematology
Megalocyte in Bone Marrow in Acute Lymphoblastic Leukemia
Bone marrow morphology in a child with acute lymphoblastic leukemia: a giant megalocyte after consolidation phase II of chemotherapy.
Parasitology
Case Study: Perianal Fold Impression Microscopy
A clinical laboratory diagnostics challenge: identify the object in a microscopic preparation of a perianal fold impression from a five-month-old child.
Hematology
Atypical Leukocyte Nuclear Shapes in Blood Smears
Peculiarities of leukocyte morphology in peripheral blood: examples of unusual heart-shaped cell nuclei observed during microscopy of stained smears.
Oncohematology
Blast Morphology in Blood Smears in Acute Leukemia
Key morphological features of blast cells in peripheral blood smears in acute leukemia: evaluating nuclear chromatin and cytoplasm structure.
Oncohematology
Granulocyte Hypersegmentation in Hydroxyurea Therapy
Clinical case: hypersegmentation of neutrophil, eosinophil, and basophil nuclei in a blood smear during hydroxyurea treatment for polycythemia vera.
Lab test interpretation
Sulfadiazine Crystals in Urine with Acute Kidney Injury
Morphology of sulfadiazine crystals in urine sediment during acute kidney injury: bright-field and polarized light microscopy of a native preparation.
Hematology
Fungi in Peripheral Blood and Bone Marrow Smears
Morphology of fungi in hematological preparations: Aspergillus in blood, Fusarium spores, and contaminants in bone marrow aspirate.
Hematology
Congenital Sideroblastic Anemia Due to HSPA9 Gene Mutation
A clinical case of congenital sideroblastic anemia with HSPA9 mutation: blood picture, dyserythropoiesis, and ring sideroblasts in bone marrow.