Clinical cases
Splendore-Hoeppli Phenomenon in Pulmonary Actinomycosis
The Splendore-Hoeppli phenomenon: causes of eosinophilic cuff formation, morphology of "sulfur granules" in pulmonary actinomycosis, and cytological diagnosis.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Oncohematology
Bone Marrow Infiltration in Chronic Lymphocytic Leukemia
Morphology of bone marrow lymphoid infiltration in chronic lymphocytic leukemia (CLL): atypical lymphocytes with cleaved nuclei, verified by immunophenotyping.
Oncohematology
Osteoblasts in Bone Marrow Smear in Acute Leukemia
A clinical case of osteoblast cluster detection in bone marrow aspirate from a patient with acute lymphoblastic leukemia. Cellular morphology features.
Laboratory methods
Leishman and Giemsa Staining of Blood and Bone Marrow Smears
Comparison of Leishman and Giemsa staining methods for blood and bone marrow smears in acute and chronic leukemias, MDS, and other hematological pathologies.
Lab test interpretation
Renal Epithelium and Epithelial Casts in Urine
Urine sediment microscopy at 400x magnification: morphology of renal epithelial cells, epithelial and hyaline casts with cellular inclusions.
Lab test interpretation
Pleural Fluid Cytology in Pleurisy and COVID-19
Morphological examination of a pleural fluid smear from a patient with pleurisy and COVID-19: differential diagnosis of effusion cells by microscopy.
Oncohematology
Atypical Pappenheimer Bodies in MDS: Differential Diagnosis
Differential diagnosis of Pappenheimer bodies and basophilic stippling in erythrocytes in myelodysplastic syndrome. Features of blood smear microscopy.
Lab test interpretation
Microscopy of Flora Smear: Inclusions in Squamous Epithelium
Analysis of flora smear microscopy: squamous epithelial cells, rod-shaped flora, and differential diagnosis of intracellular inclusions versus staining artifacts.
Lab test interpretation
Stool Microscopy: Differentiating Plant Fiber and Muscle Fibers
Learn the specifics of stool microscopy: differentiating undigested plant fiber from muscle fibers in a native preparation during coprological examination.
Clinical cases
Renal Cell Carcinoma Metastasis to Cervical Lymph Node
Cytological findings of a cervical lymph node aspirate in renal cell carcinoma metastasis: atypical epithelial cells and differential diagnosis.
Hematology
Severe Neutropenia in a Child: A Clinical Case Study
Clinical case: a one-year-old child presents with agranulocytosis, rash, and fever. Evaluate the complete blood count, possible causes, and emergency measures.
Hematology
Plasmacyte or Plasmacytoid Lymphocyte: Blood Smear Challenge
A morphological hematology exercise: identify which numbered cell in the blood smear is a plasmacytoid lymphocyte and which is a plasma cell.