Clinical cases
Cytology Exercise: Cell Changes in a Pap Test
A diagnostic cytology exercise: determine the cause of epithelial changes in a cervical Pap test from a 50-year-old woman. Test your knowledge.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Parasitology
Microsporidia: Spore Morphology in Corneal Section
Morphology and microscopic identification of microsporidia spores in corneal sections. Giemsa stain, polar tube extrusion, and main causative agents.
Laboratory methods
Automated Blood Smear Staining with Sysmex SP-10
Application of the Sysmex SP-10 automated system for standardized blood smear preparation and staining in a clinical diagnostic laboratory.
Lab test interpretation
Algorithm for Differential Diagnosis of Hypomagnesemia
A laboratory algorithm for the differential diagnosis of hypomagnesemia based on the assessment of urinary magnesium excretion, extrarenal, and renal losses.
Parasitology
Microscopy of Giardia lamblia Cysts in Feces
Morphology and laboratory identification of Giardia lamblia cysts by microscopy of fecal emulsion with Lugol's solution for giardiasis diagnosis.
Oncohematology
Blastic Plasmacytoid Dendritic Cells in Lymph Node
Morphological features of blastic plasmacytoid dendritic cells in a lymph node. Diagnostic characteristics and differentiation.
Parasitology
Identifying Trichomonads in Smear Microscopy
Features of detecting Trichomonas vaginalis in smear microscopy: differential diagnosis with leukocytes amidst pronounced inflammation.
Hemostasis
Differential Diagnosis of Thrombocytosis in Complete Blood Count
What to do when thrombocytosis exceeds 450,000/µL: common causes of reactive platelet elevation, the role of ferritin and CRP, and indications for genetic tests.
Oncohematology
Blasts in a Child's Blood Smear: A Case of Acute Leukemia
Clinical case of acute leukemia in a child: 55% blasts, anemia, thrombocytopenia, scattergrams, and digital microscopy data from a blood analyzer.
Hematology
Band Neutrophils in Marked Leukocytosis: A Case Study
Morphological assessment of neutrophils and differentiation of band forms in a peripheral blood smear during marked leukocytosis (WBC 28.3×10⁹/L).
Laboratory methods
Perls' Reaction in Sputum: Heart Failure Cells
Perls' reaction for hemosiderin detection in sputum. Diagnostic significance of siderophages (heart failure cells) in pulmonary congestion.
Lab test interpretation
Neutral Fat in Coprogram: Sudan III Staining for Steatorrhea
Detection of neutral fat in stool using Sudan III staining. Microscopic signs of steatorrhea, causes of lipid malabsorption, and diagnostic approaches.